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This research uses induced pluripotent stem cell-derived models of heart valve tissue to understand the role the immune system plays in Rheumatic heart disease (RHD) and advance treatments to improve the lives of people living with RHD.
BANDICOOT is a world‑first adaptive platform trial dedicated to improving the health outcomes of critically ill children undergoing haematopoietic stem cell transplant (HCT), also known as a bone marrow transplant. Using an innovative adaptive platform trial design, BANDICOOT can test multiple
Following the completion of our priority setting partnership, we have pleased to announce the top 10 research priorities for paediatric haematopoietic stem cell transplant. This study is designed to improve the lives of children who are undergoing a bone marrow transplant (BMT).
The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), led by Murdoch Children’s Research Institute Chief Scientist Professor Melissa Little, has released its first annual report. The report highlights the work accomplished by reNEW, a global consortium that focuses on translating
Promoting cardioprotection in stem cell models of cardiotoxic heart damage from cancer patients. ACOR is a world's first paediatric and young adult prospective cardio-oncology registry designed to capture the clinical, epidemiological and pharmaceutical data from every Australian child and young
This study seeks to understand the cellular and molecular events that follow a respiratory infection, to find new therapeutic approaches.
This study aims to uncover the signals that govern the balance between effective lung repair and maladaptive fibrosis following respiratory viral infections, with the goal of identifying therapeutic targets to improve recovery and prevent long-term pulmonary fibrosis.
Wearable technology and machine learning (AI) for early detection and risk assessment of unacceptable toxicities in paediatric oncology. This is a PhD project.
We are investigating perspectives into gene therapy for parents of children with severe combined immunodeficiency (SCID). Gene therapy is a technique that modifies a patient’s genes to help treat or cure diseases such as severe combined immunodeficiency (SCID). To learn more about people’s
MARVEL-PIC aims to assess whether prescribing medications according to pharmacogenomic (PGx) test results and international PGx guidelines is cost-effective and reduces adverse drug reactions in paediatric oncology patients.
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